Overtreatment of older people with type 2 diabetes—a high impact frequent occurrence in need of a new definition
Authors' conclusion
Definitions of diabetes overtreatment are heterogeneous across research studies, which is confusing. A standardised definition, based on the individual risk of hypoglycaemia and/or its complications must be promoted in order to bring clarity and greater insight into this field, as well as to improve the quality of management of diabetes in older patients.
Study context
- Population
- Research studies addressing diabetes overtreatment in people aged 65 or older with T2D22 studies
- Outcome
- Definitions of diabetes overtreatment in older people used in research studies
Methodological detailsPubMed search
- PubMed search
Main finding
As reported in the abstract
Definitions of diabetes overtreatment
- Studies providing a definition of overtreatment
- 22
- Different definitions used
- 12
- All studies defined overtreatment by an HbA1c threshold
- <42 mmol/mol [<6.0%] to <64 mmol/mol [<8%]
- Definitions with no consideration of glucose-lowering treatment
- 2
- Definitions requiring ≥1 glucose-lowering agent
- 6
- Definitions requiring ≥1 glucose-lowering agent at high risk of hypoglycaemia (SU or insulin)
- 4
- Individualised definitions (HbA1c thresholds by age or health status)
- 4 definitions (four studies)
Original publication
Overtreatment of older people with type 2 diabetes—a high impact frequent occurrence in need of a new definition. Diabet Med. Published 6 November 2022. doi:10.
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