An Observational Crossover Study of People Using Real-Time Continuous Glucose Monitors Versus Self-Monitoring of Blood Glucose: Real-World Evidence Using Electronic Medical Record Data From More Than 12,000 People With Type 1 Diabetes
Authors' conclusion
We found that people who switched to CGM use had significantly improved HbA1c levels compared to those who switched to glucose monitoring with SMBG.
Study context
- Population
- Children and adults with T1D, electronic medical record (EMR) data from the T1D Exchange Quality Improvement Collaborative, 5-year study time frame
- Participants
- 7,706 vs 5,123
- Exposure
- Switch from self-monitoring of blood glucose (SMBG) to continuous glucose monitor (CGM) vs switch from CGM to SMBG
- SMBG to CGMn = 7,706
- CGM to SMBGn = 5,123reference
- Outcome
- HbA1c
Methodological detailsreal-world EMR data, T1D Exchange Quality Improvement Collaborative
- Real-world EMR data
- T1D Exchange Quality Improvement Collaborative
Main finding
As reported in the abstract
HbA1c, baseline vs postcrossover
- SMBG to CGM: median (IQR) HbA1c at baseline 8.1 (2.4), declined postcrossover to 7.7 (1.9); P < .001
- CGM to SMBG: median (IQR) HbA1c at baseline 7.9 (2.0), increased postcrossover to 8.0 (2.9); P < .001
Observational data: associations, not effects.
Original publication
An Observational Crossover Study of People Using Real-Time Continuous Glucose Monitors Versus Self-Monitoring of Blood Glucose: Real-World Evidence Using Electronic Medical Record Data From More Than 12,000 People With Type 1 Diabetes. J Diabetes Sci Technol. Published 1 June 2023. doi:10.
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