Metabolically healthy obesity is independently associated with 20-year incidence of cardiovascular disease: findings from the ATTICA cohort study (2002–2022)
Authors' conclusion
Individuals with MUO exhibit the highest risk, but individuals with MHO also have an independently increased CVD risk, emphasizing the significant impact of both obesity and metabolic health status on long-term CVD incidence.
Study context
- Population
- Adults from the Attica region, Greece, categorised by obesity and metabolic health status
- Participants
- 3,042 adults
- Exposure
- Obesity/metabolic health phenotypes
- Outcome
- CVD incidence
- Follow-up
- 20 years
Main finding
As reported in the abstract
Incident CVD · 20-year follow-up
Metabolically unhealthy obesity (MUO)
61.1%
Each group vs MHWOHazard ratio (95% CI)
MUO85% higher risk
1.85(1.02–3.58)
MHO39% elevated risk
1.39(1.06–3.42)
- Participants with a cardiovascular disease (CVD) event
- 718
Observational data: associations, not effects.
Original publication
Metabolically healthy obesity is independently associated with 20-year incidence of cardiovascular disease: findings from the ATTICA cohort study (2002–2022). Int J Obes (Lond). Published 18 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →