Mediators of the Association Between Child Education and Adult Health

JAMA Netw OpenPublished Birth cohort study

Authors' conclusion

In this birth cohort study, results showed that associations between educational experiences in childhood and cardiometabolic health in adulthood were mediated by adult income for 4 of 5 indicators and by adult diet for 2 of 5 indicators. This suggests that, across diverse educational experiences, long-term health benefits may be transmitted through having a higher adult income and a healthier adult diet. Findings offer a developmental framework for understanding the well-established education-health gradient, highlighting opportunities for early health promotion.

Study context

Population
Participants of the NICHD Study of Early Child Care and Youth Development (SECCYD), birth cohort (1991–2009), assessed at ages 26–31 (2018–2022); mean age 28.6 years, 53.4% female
Participants
700 participants
Exposure
Child educational indicators and adult cardiometabolic risk, mediated by adult socioeconomic status and health behaviors
Outcome
Composite metabolic syndrome index of cardiometabolic risk (CMR):
  • Waist circumference
  • Systolic and diastolic BP
  • HbA1c
  • C-reactive protein
  • HDL
Follow-up
30-year assessment (ages 26-31)
Methodological detailsmediation analysis, linear regression models
  • Mediation analysis
  • Linear regression models

Main finding

As reported in the abstract

Mediation of child educational indicators–adult CMR associations
Adult income mediated student social competence–adult cardiometabolic risk (CMR) association: b (95% CI); P
−0.001 (−0.002 to −0.0003); P = .02
Adult income mediated student-teacher relationship quality–adult CMR association: b (95% CI); P
−0.002 (−0.004 to −0.001); P = .02
Adult income mediated classroom instructional quality–adult CMR association: b (95% CI); P
−0.012 (−0.034 to −0.001); P = .06 for trend
Adult income mediated academic achievement–adult CMR association: b (95% CI); P
−0.001 (−0.002 to −0.0004); P = .02
Adult diet quality mediated student social competence–adult CMR association: b (95% CI); P
−0.002 (−0.004 to −0.001); P < .001
Adult diet quality mediated student-teacher relationship quality–adult CMR association: b (95% CI); P
−0.003 (−0.005 to −0.001); P = .01

Observational data: associations, not effects.

Original publication

Mediators of the Association Between Child Education and Adult Health. JAMA Netw Open. Published 1 May 2025. doi:10.1001/jamanetworkopen.2025.8855

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