Long-term Performance of a Dynamic Clinical Decision Support System for Intravenous Insulin Therapy: A Retrospective Cohort Study in Patients With and Without Diabetes
Authors' conclusion
Use of Glucopilot, an electronic medical record-integrated adaptive insulin dosing software, was associated with timely attainment of euglycemia and sustained glycemic control with a median of 0% time in hypoglycemia in real-world practice.
Study context
- Population
- Adults receiving intravenous (IV) insulin guided by Glucopilot at 9 hospitals, Aug 2020–May 2025; admissions with <10 hours IV insulin or insufficient glucose monitoring excluded
- Participants
- 1,239 admissions
- Outcome
- Glycemic performance
Methodological detailsmulticentre (9 hospitals), real-world
- Multicentre (9 hospitals)
- Real-world
Main finding
As reported in the abstract
- Time to euglycemia (all patients presenting with hyperglycemia achieved euglycemia)
- median 174 minutes
- Time in euglycemia after attainment
- median 96%
- Time in hyperglycemia
- median 4%
- Time in hypoglycemia
- median 0%
- Sustained euglycemia (100% time in euglycemia after initial attainment)
- 43.4% of admissions
Observational data: associations, not effects.
Further findings
Factors associated with glycemic control
- Steroid use was not associated with reduced likelihood of sustained euglycemia
- Baseline glucose strongly associated with time to euglycemia but not with subsequent time in euglycemia
- Glycemic control consistent across subgroups
Safety
- Median time in hypoglycemia
- 0%
Original publication
Long-term Performance of a Dynamic Clinical Decision Support System for Intravenous Insulin Therapy: A Retrospective Cohort Study in Patients With and Without Diabetes. J Diabetes Sci Technol. Published 21 July 2026. doi:10.
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