Joint association of atherogenic index of plasma (AIP) and body roundness index (BRI) with cardiometabolic multimorbidity in adults in Guangzhou, China
Authors' conclusion
Individuals with elevated levels of AIP and BRI are more likely to have CMM. AIP is linearly associated with CMM, whereas a threshold effect is observed for BRI. The joint assessment of AIP and BRI demonstrates a stronger association with CMM compared to either indicator alone. These findings suggest that the joint assessment of AIP and BRI may be a useful tool for identifying individuals at a higher likelihood of prevalent CMM, particularly in young and middle-aged adults.
Study context
- Population
- Adults from the 2024 Guangzhou Residents' Nutrition Survey, China
- Participants
- 2,505 adults
- Exposure
- Highest vs lowest tertile of AIP and BRI; joint AIP/BRI groups
- Outcome
- Cardiometabolic multimorbidity (CMM)
Main finding
As reported in the abstract
CMM
Odds ratio (95% CI)
Highest tertile of AIPvs Lowest tertile of AIP
4.025(2.591–6.455)
Highest tertile of BRIvs Lowest tertile of BRI
10.461(5.523–22.496)
High AIP+high BRIvs Lowest tertilestrongest association with CMM among the four joint groups
5.081(3.354–7.828)
- Cardiometabolic multimorbidity (CMM) prevalence
- 213 (8.50%)
- BRI nonlinear association with CMM; inflection point, below which odds of CMM increased more rapidly
- 4.52
Observational data: associations, not effects.
Further findings
Subgroup by age: high AIP+high BRI and CMM
- Association stronger in participants < 60 years
Original publication
Joint association of atherogenic index of plasma (AIP) and body roundness index (BRI) with cardiometabolic multimorbidity in adults in Guangzhou, China. Cardiovasc Diabetol. Published 17 May 2026. doi:10.
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