Obesity

Interaction Between Genetic Risk and Parental Feeding Practices in the Prediction of Overweight Across Adolescence

Obesity (Silver Spring)Published Prospective cohort study

Authors' conclusion

Genetic risk and parental feeding practices were independently associated with adolescent weight development.

Study context

Population
Participants aged 10–18 in the Twins' Early Development Study with ≥1 weight measurement; feeding practices reported at age 10 (Child Feeding Questionnaire)
Participants
5,568 participants
Exposure
Genetic risk, parental feeding practices and their interactions
Outcome
Overweight trajectory during adolescence
Follow-up
Age 10–18
Methodological detailstwin cohort, latent class growth analysis, multinomial logistic regression
  • Twin cohort
  • Latent class growth analysis
  • Multinomial logistic regression

Main finding

As reported in the abstract

Associations with overweight trajectories
  • Three trajectories identified: non-overweight, persistent overweight and adolescent-onset overweight
  • Higher genetic risk and greater parental restriction and monitoring associated with persistent overweight
  • Pressure to eat associated with non-overweight
  • Associations remained after adjustment for general parenting and additional risk factors
  • No evidence for gene-environment interaction

Observational data: associations, not effects.

Original publication

Interaction Between Genetic Risk and Parental Feeding Practices in the Prediction of Overweight Across Adolescence. Obesity (Silver Spring). Published 11 May 2026. doi:10.1002/oby.70217

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