Insights into the effective use of the Smart Multiple Daily Insulin (MDI) system: Data from the first 1852 type 1 diabetes users
Authors' conclusion
User engagement with the Smart MDI system is crucial for optimal glycaemic outcomes. The study underscores the need for structured education on system use and alert responses. While causality cannot be confirmed, the findings suggest that proactive user interactions contribute to meeting glycaemic targets. Further research is needed to explore these relationships and enhance educational strategies.
Study context
- Population
- People with T1D using the Smart MDI system (InPen insulin injector, Simplera CGM, InPen app) with ≥10 days of InPen and CGM data, 21 countries
- Participants
- 1,852 people
- Exposure
- Responsiveness to missed dose alerts (MDA) and correct high glucose alerts (CHGA) alerts vs glycaemic outcomes
- Outcome
- TIR and alert responsiveness
Methodological detailsreal-world data, 21 countries
- Real-world data
- 21 countries
Main finding
As reported in the abstract
- Mean time in range (TIR), all users
- 55.7%
- MDA responded to with a bolus dose
- 49.3%
- CHGA responded to with a bolus dose
- 46.6%
- TIR in users responding within 1 h to >75% of MDA with a bolus
- 67.2%
- TIR in users responding within 1 h to >75% of CHGA with a bolus
- 71.5%
Observational data: associations, not effects.
Original publication
Insights into the effective use of the Smart MDI system: Data from the first 1852 type 1 diabetes users. Diabet Med. Published 13 October 2025. doi:10. 1111/ dme. 70161
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