Diabetes technology

Insights into the effective use of the Smart Multiple Daily Insulin (MDI) system: Data from the first 1852 type 1 diabetes users

Diabet MedPublished Retrospective cohort study

Authors' conclusion

User engagement with the Smart MDI system is crucial for optimal glycaemic outcomes. The study underscores the need for structured education on system use and alert responses. While causality cannot be confirmed, the findings suggest that proactive user interactions contribute to meeting glycaemic targets. Further research is needed to explore these relationships and enhance educational strategies.

Study context

Population
People with T1D using the Smart MDI system (InPen insulin injector, Simplera CGM, InPen app) with ≥10 days of InPen and CGM data, 21 countries
Participants
1,852 people
Exposure
Responsiveness to missed dose alerts (MDA) and correct high glucose alerts (CHGA) alerts vs glycaemic outcomes
Outcome
TIR and alert responsiveness
Methodological detailsreal-world data, 21 countries
  • Real-world data
  • 21 countries

Main finding

As reported in the abstract

Mean time in range (TIR), all users
55.7%
MDA responded to with a bolus dose
49.3%
CHGA responded to with a bolus dose
46.6%
TIR in users responding within 1 h to >75% of MDA with a bolus
67.2%
TIR in users responding within 1 h to >75% of CHGA with a bolus
71.5%

Observational data: associations, not effects.

Original publication

Insights into the effective use of the Smart MDI system: Data from the first 1852 type 1 diabetes users. Diabet Med. Published 13 October 2025. doi:10.1111/dme.70161

Composed by AI from the published abstract and checked against it. How Briefs are made →

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