Incidence and Geographical Distribution of Adrenocortical Carcinoma: Retrospective Analysis of a State Cancer Registry
Authors' conclusion
Our analysis is the first report to create ACC heatmap and could not detect any geographic clustering of ACC in Texas. The incidence of ACC remained stable and consistent with data from other large databases.
Study context
- Population
- Patients with adrenocortical carcinoma (ACC) diagnosed 2000–2018, Texas Cancer Registry
- Participants
- 448 ACC cases
- Outcome
- ACC incidence and county-level geographic distribution
Methodological detailsstate cancer registry, county-level heatmaps, Heatmaps compared with breast, prostate and lung cancer
- State cancer registry
- County-level heatmaps
- Heatmaps compared with breast, prostate and lung cancer
Main finding
As reported in the abstract
ACC incidence · 2000–2018
- Median incidence, new cases/y (range 14-33)
- 23
- Mean population-adjusted ACC incidence rate per 100 000 per year
- 0.104 (SD 0.005; 95% CI, 0.092-0.116)
- Counties with registered cases
- 110 of the 254 counties (43.3%)
- Seven counties (6.3%), >10 cases each: cases
- 215 (48.0%)
- Median standardized incidence ratio (SIR) in these 7 counties (range, 0.0-0.9)
- 0.1
- 103 counties (93.7%), <10 cases each: cases
- 233 (52%)
Observational data: associations, not effects.
Original publication
Incidence and Geographical Distribution of Adrenocortical Carcinoma: Retrospective Analysis of a State Cancer Registry. Endocr Pract. Published 18 October 2023. doi:10.
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