Type 2 & other diabetes

Implications of the Glycemia Risk Index in Assessing Metabolic Control and Its Correlation With Therapy-Related Quality of Life During-Ramadan Fasting in Adults With Type 2 Diabetes

J Diabetes Sci TechnolPublished Ambispective one-group pre-post study

Authors' conclusion

With tailored education and CGM-based monitoring, Ramadan fasting can improve glycemia in individuals with T2D, enhancing GRI and related glycometric parameters for safer, more stable glycemic patterns.

Study context

Population
Adults with T2D fasting during Ramadan, tertiary diabetes treatment center
Participants
111 adults
Comparison
Before vs during vs after Ramadan fasting
Outcome
Glycemia risk index (GRI) from continuous glucose monitoring (CGM) data
Methodological detailssingle-centre, tertiary diabetes treatment center
  • Single-centre
  • Tertiary diabetes treatment center

Main finding

As reported in the abstract

GRI

Before

35.2

During

30.5

median

After

37.4

P < 0.001

Further findings

OutcomeBeforeDuringP value
%TIR70-180During vs Before42%66%P < 0.001

Glycemia risk index (GRI) hypoglycemia (CHypo) and hyperglycemia (CHyper) components

Both CHypo and CHyper significantly reduced during fasting

%TIR70-180

Notable decrease in glycemic variability

Diabetes therapy-related quality of life (DTR-QOL) scale score

DTR-QOL scale score, high across all domains
78.3 (IQR 75.4-81.3)
No significant differences across GRI zones

Original publication

Implications of the Glycemia Risk Index in Assessing Metabolic Control and Its Correlation With Therapy-Related Quality of Life During-Ramadan Fasting in Adults With Type 2 Diabetes. J Diabetes Sci Technol. Published 28 February 2025. doi:10.1177/19322968251321860

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