Implications of the Glycemia Risk Index in Assessing Metabolic Control and Its Correlation With Therapy-Related Quality of Life During-Ramadan Fasting in Adults With Type 2 Diabetes
Authors' conclusion
With tailored education and CGM-based monitoring, Ramadan fasting can improve glycemia in individuals with T2D, enhancing GRI and related glycometric parameters for safer, more stable glycemic patterns.
Study context
- Population
- Adults with T2D fasting during Ramadan, tertiary diabetes treatment center
- Participants
- 111 adults
- Comparison
- Before vs during vs after Ramadan fasting
- Outcome
- Glycemia risk index (GRI) from continuous glucose monitoring (CGM) data
Methodological detailssingle-centre, tertiary diabetes treatment center
- Single-centre
- Tertiary diabetes treatment center
Main finding
As reported in the abstract
GRI
Before
35.2
During
30.5
median
After
37.4
P < 0.001
Further findings
| Outcome | Before | During | P value |
|---|---|---|---|
| %TIR70-180During vs Before | 42% | 66% | P < 0.001 |
Glycemia risk index (GRI) hypoglycemia (CHypo) and hyperglycemia (CHyper) components
- Both CHypo and CHyper significantly reduced during fasting
%TIR70-180
- Notable decrease in glycemic variability
Diabetes therapy-related quality of life (DTR-QOL) scale score
- DTR-QOL scale score, high across all domains
- 78.3 (IQR 75.4-81.3)
- No significant differences across GRI zones
Original publication
Implications of the Glycemia Risk Index in Assessing Metabolic Control and Its Correlation With Therapy-Related Quality of Life During-Ramadan Fasting in Adults With Type 2 Diabetes. J Diabetes Sci Technol. Published 28 February 2025. doi:10. 1177/ 19322968251321860
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