Impact of Simplera Sync™ sensors and Extended™ Wear Infusion Sets on glycaemia and system performance of the MiniMed ™ 780G system in children and young adults with previously high HbA1c
Authors' conclusion
Simplera Sync™ and EIS improved time in automation and sensor wear time when using 780G AHCL in this high-risk young population. This was associated with incremental improvement in time in tight range despite the challenges of this population.
Study context
- Population
- Young people aged 7–25 years with T1D and previously elevated HbA1c (≥69 mmol/mol [≥8%]) using MiniMed 780G
- Participants
- 75 people
- Comparison
- 780G with Simplera Sync and 7-day EIS vs 780G with Guardian 4 sensors and 3-day infusion sets
Methodological detailsbefore-after comparison
- Before-after comparison
Primary result
As reported in the abstract
HbA1c
P = 0.38
Further findings
| Outcome | Simplera Sync + EIS | Baseline | P value |
|---|---|---|---|
| TIR (3.9-10.0 mmol/L [70-180 mg/dL]) | 60.4% ± 15.7% | 58.5% ± 14.9% | P = 0.09 |
| Time in tight range (3.9-7.8 mmol/L [70-140 mg/dL])Increased | 40.5% ± 13.6% | 38.1% ± 13.1% | P = 0.04 |
| Automation timeIncreased | 85.8% ± 21.8% | 79.2% ± 25.9% | P = 0.007 |
| Sensor wear timeIncreased | 88.4% ± 17.2% | 80.7% ± 22.4% | P < 0001 |
Original publication
Impact of Simplera Sync™ sensors and Extended™ Wear Infusion Sets on glycaemia and system performance of the MiniMed ™ 780G system in children and young adults with previously high HbA1c. Diabet Med. Published 18 April 2025. doi:10.
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