Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study
Authors' conclusion
MBS was associated with substantial metabolic improvement in people with T1D and obesity, in particular in those with high HbA1c and insulin need at baseline.
Study context
- Population
- People living with T1D and obesity undergoing metabolic bariatric surgery (MBS)
- Participants
- 162 people
- Exposure
- Before vs after MBS
- MBSn = 162
- Outcome
- Total weight loss
- Follow-up
- 1 year after surgery
Methodological detailsmulticenter
- Multicenter
Main finding
As reported in the abstract
After surgery
29.7
mean · IQR 29.4–30.3 · %
Observational data: associations, not effects.
Further findings
Daily insulin requirement · before surgery to one year after surgery
- Insulin requirements dropped from 0.75 (IQR = 0.58, 1.00) to 0.32 (IQR = 0.23, 0.43) units/kg/day
- P < 0.001
HbA1c · before surgery to one year after surgery
- HbA1c dropped from 64.0 (IQR = 57.0, 74.0) to 60.0 (IQR = 53.4, 68.0) mmol/mol
- P < 0.001
LDL, HDL, total cholesterol and TG · after surgery
- LDL, HDL, total cholesterol and TG levels significantly improved after surgery
- P < 0.001
Response determinants
- Greater total weight loss associated with reduced insulin requirements
- Higher baseline HbA1c associated with poorer postsurgery glycemic control
- Longitudinal models
Original publication
Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study. Diabetes Care. Published 18 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →