Impact of Infusion Set Materials and Designs on the Subcutaneous Response in People With Diabetes: A Rapid Review of the Literature
Authors' conclusion
Reports on materials mostly compared steel versus polytetrafluoroethylene (Teflon) cannulas and suggested no substantial difference in tissue response to these materials.
Study context
- Population
- People with diabetes using insulin infusion sets for CSII; literature from PubMed, Embase and Cochrane
- Participants
- 21 studies
- Comparison
- IIS materials and designs
- Outcome
- Subcutaneous tissue response to IIS materials
Methodological detailsqualitative synthesis
- Qualitative synthesis
Main finding
As reported in the abstract
- No substantial difference in tissue response to steel vs Teflon cannulas suggested
- Reports on designs focused mostly on angle of cannula insertion
Further findings
Composition of evidence
- Clinical reports
- 10
- Reviews
- 6
- Case report
- 1
- Abstracts
- 2
- Communications
- 2
- Randomized crossover studies among clinical reports
- 2
- Limited and heterogenic body of evidence
Original publication
Impact of Infusion Set Materials and Designs on the Subcutaneous Response in People With Diabetes: A Rapid Review of the Literature. J Diabetes Sci Technol. Published 18 November 2022. doi:10. 1177/ 19322968221138076
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