Diabetes technology

Impact of Infusion Set Materials and Designs on the Subcutaneous Response in People With Diabetes: A Rapid Review of the Literature

J Diabetes Sci TechnolPublished Rapid review

Authors' conclusion

Reports on materials mostly compared steel versus polytetrafluoroethylene (Teflon) cannulas and suggested no substantial difference in tissue response to these materials.

Study context

Population
People with diabetes using insulin infusion sets for CSII; literature from PubMed, Embase and Cochrane
Participants
21 studies
Comparison
IIS materials and designs
Outcome
Subcutaneous tissue response to IIS materials
Methodological detailsqualitative synthesis
  • Qualitative synthesis

Main finding

As reported in the abstract

  • No substantial difference in tissue response to steel vs Teflon cannulas suggested
  • Reports on designs focused mostly on angle of cannula insertion

Further findings

Composition of evidence

Clinical reports
10
Reviews
6
Case report
1
Abstracts
2
Communications
2
Randomized crossover studies among clinical reports
2
  • Limited and heterogenic body of evidence

Original publication

Impact of Infusion Set Materials and Designs on the Subcutaneous Response in People With Diabetes: A Rapid Review of the Literature. J Diabetes Sci Technol. Published 18 November 2022. doi:10.1177/19322968221138076

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