Impact of Age ≥75 Years on Glycemic Outcomes After Intermittently Scanned Continuous Glucose Monitoring (isCGM) Initiation in Type 2 Diabetes: Evidence Against Ageism in a Universal-Coverage System
Authors' conclusion
In a publicly funded system, isCGM use was associated with clinically meaningful HbA1c reductions in T2D patients on multiple daily insulin injections, with no attenuation among adults ≥75 years. Chronological age should not restrict isCGM prescription; policies should address ageism and ensure equitable access for older adults.
Study context
- Population
- Adults with T2D on MDI who initiated isCGM, 3 hospitals, universal-coverage health system; mean age 67.3 ± 10.4 years; 22.9% ≥75384 with paired hemoglobin A1c (HbA1c)
- Participants
- 402 adults
- Comparison
- Age ≥75 vs <75 years after isCGM initiation
- Primary endpoint
- HbA1c change (post vs pre isCGM initiation) by age group (age × time interaction)
- Follow-up
- ≤1 month preinitiation and ≥3 months post-initiation
Methodological details3 hospitals, mixed-effects linear regression
- 3 hospitals
- Mixed-effects linear regression
Primary result
As reported in the abstract
HbA1c change after isCGM initiation by age group (age × time interaction) · ≥3 months post-initiation
- Age ≥75 vs <75 years: β −0.388; 95% CI −0.988 to 0.213; P = .206 (not significant)
- Age × time interaction: β 0.164; 95% CI −0.199 to 0.527; P = .376 (not significant), indicating similar benefit
- Time (post vs pre) predicted lower HbA1c: β −0.843; 95% CI −1.016 to −0.669; P < .001
- Adjusted mixed-effects linear regression
- Post hoc subanalysis
Further findings
Overall HbA1c pre vs post isCGM initiation · ≥3 months post-initiation
- Overall HbA1c fell from 8.5 ± 1.5% to 7.7 ± 1.1%
- P < 0.001
- Time (post vs pre) predicted lower HbA1c, adjusted β
- −0.843 (95% CI −1.016 to −0.669; P < .001)
Original publication
Impact of Age ≥75 Years on Glycemic Outcomes After Intermittently Scanned Continuous Glucose Monitoring (isCGM) Initiation in Type 2 Diabetes: Evidence Against Ageism in a Universal-Coverage System. Endocr Pract. Published 7 January 2026. doi:10.
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