Diabetes technology

Hypoglycaemia Thresholds in Children with Type 1 Diabetes: Real-Life Practices in the Era of Diabetes Technology

Horm Res PaediatrPublished Cross-sectional study

Authors' conclusion

Parents and children personalise the glucose thresholds for commencing hypoglycaemia treatment based on the clinical context. Although these thresholds did not increase the time in hypoglycaemia

Study context

Population
Children with T1D (parent if child <12 years), Western Australian Children's Diabetes Database; median age 13.4 years, 98% CGM
Participants
271 survey respondents
Exposure
Hypoglycaemia treatment at vs below vs above the recommended threshold
Outcome
Chosen glucose thresholds for hypoglycaemia treatment
Methodological detailsonline survey, linked clinical database
  • Online survey
  • Linked clinical database

Main finding

As reported in the abstract

Hypoglycaemia treatment threshold
Adoption of thresholds independent of mode of insulin delivery
P = 0.54

Observational data: associations, not effects.

Further findings

Threshold adjustment and use of CGM trend arrows

Adjusted thresholds by day/night
37.3%
Adjusted thresholds by active insulin on board
56.1%
Adjusted thresholds by exercise
83.8%
Used CGM trend arrows to guide treatment
96.2%

HbA1c, TIR, time below range (TBR), hypoglycaemia awareness and fear of hypoglycaemia scores

No evidence of a difference between the three groups
P > 0.05

Achievement of target TBR <3.9 mmol/L (<4%)

Those treating above recommended threshold (RT) achieved target TBR than other groups
P < 0.05

Safety

Events

OutcomeRTBelow RT
Severe hypoglycaemia21
Severe hypoglycaemia — Episodes of severe hypoglycaemia
3

Original publication

Hypoglycaemia Thresholds in Children with Type 1 Diabetes: Real-Life Practices in the Era of Diabetes Technology. Horm Res Paediatr. Published 4 September 2026. doi:10.1159/hrp/adaag013

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