Hypoglycaemia Thresholds in Children with Type 1 Diabetes: Real-Life Practices in the Era of Diabetes Technology
Authors' conclusion
Parents and children personalise the glucose thresholds for commencing hypoglycaemia treatment based on the clinical context. Although these thresholds did not increase the time in hypoglycaemia
Study context
- Population
- Children with T1D (parent if child <12 years), Western Australian Children's Diabetes Database; median age 13.4 years, 98% CGM
- Participants
- 271 survey respondents
- Exposure
- Hypoglycaemia treatment at vs below vs above the recommended threshold
- Outcome
- Chosen glucose thresholds for hypoglycaemia treatment
Methodological detailsonline survey, linked clinical database
- Online survey
- Linked clinical database
Main finding
As reported in the abstract
Hypoglycaemia treatment threshold
- Adoption of thresholds independent of mode of insulin delivery
- P = 0.54
Observational data: associations, not effects.
Further findings
Threshold adjustment and use of CGM trend arrows
- Adjusted thresholds by day/night
- 37.3%
- Adjusted thresholds by active insulin on board
- 56.1%
- Adjusted thresholds by exercise
- 83.8%
- Used CGM trend arrows to guide treatment
- 96.2%
HbA1c, TIR, time below range (TBR), hypoglycaemia awareness and fear of hypoglycaemia scores
- No evidence of a difference between the three groups
- P > 0.05
Achievement of target TBR <3.9 mmol/L (<4%)
- Those treating above recommended threshold (RT) achieved target TBR than other groups
- P < 0.05
Safety
Events
| Outcome | RT | Below RT |
|---|---|---|
| Severe hypoglycaemia | 2 | 1 |
- Severe hypoglycaemia — Episodes of severe hypoglycaemia
- 3
Original publication
Hypoglycaemia Thresholds in Children with Type 1 Diabetes: Real-Life Practices in the Era of Diabetes Technology. Horm Res Paediatr. Published 4 September 2026. doi:10. 1159/ hrp/ adaag013
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