Hypoglycaemia symptom frequency, severity, burden, and utility among adults with type 1 diabetes and impaired awareness of hypoglycaemia: Baseline and 24‐week findings from the HypoCOMPaSS study
Authors' conclusion
Adults with T1D and IAH experience a range of hypoglycaemia symptoms. Perceptions of symptom burden or utility are malleable. Although larger scale studies are needed to confirm, these findings suggest that changing the salience of the symptomatic response may be more important in recovering protection from hypoglycaemia through regained awareness than intensifying symptom frequency or severity.
Study context
- Population
- Adults with T1D (duration 29 ± 12 years; 64% women) and impaired awareness of hypoglycaemia (IAH)
- Participants
- 96 adults
- Comparison
- Baseline vs week 24 following the HypoCOMPaSS awareness restoration intervention
- Primary endpoint
- Frequency, severity, burden and utility of hypoglycaemia symptoms (Hypoglycaemia Burden Questionnaire, 20 pre-specified symptoms)
- Follow-up
- Baseline and week 24
Primary result
As reported in the abstract
Hypoglycaemia symptoms at baseline
Experienced at least one symptom
93
97%
Number of symptoms, mean ± SD
10.6 ± 4.6
Proportion recognising each specific symptom
15% to 83%
Further findings
Symptom severity, burden and utility · 24 weeks
- Symptom severity and burden appear reduced, and utility increased
Original publication
Hypoglycaemia symptom frequency, severity, burden, and utility among adults with type 1 diabetes and impaired awareness of hypoglycaemia: Baseline and 24‐week findings from the HypoCOMPaSS study. Diabet Med. Published 9 October 2023. doi:10.
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