High prevalence of sarcopenia, osteoporosis and osteosarcopenia in patients with chronic kidney disease compared with healthy controls
Main finding · Osteosarcopenia prevalenceResult — go to the resultOdds ratio 6.44 CI 1.39–60.4Authors' conclusion
In this cross-sectional study, there was a higher prevalence of sarcopenia, osteoporosis, and osteosarcopenia in patients with CKD as compared to sex- and age-matched healthy controls.
Study context
- Population
- Patients with non-dialysis-dependent chronic kidney disease (CKD) stages G4–5 and sex- and age-matched healthy controls1:1 matched
- Exposure
- Non-dialysis CKD stages G4-5 vs sex- and age-matched healthy controls
- CKDn = 138
- Outcome
- Prevalence of osteosarcopenia (EWGSOP sarcopenia plus WHO osteoporosis)
Methodological detailsmatched 1:1 on sex and age
- Matched 1:1 on sex and age
Main finding
Osteosarcopenia prevalence
Odds ratio
6.44
CI 1.39–60.4
By group
CKDvs Healthy controls
OR 6.44 (CI 1.39–60.4)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | CKD | Healthy controls | OR (CI) | |
|---|---|---|---|---|
| Sarcopenia prevalence | 21.7% | 5.8% | 4.51 (1.91–11.8) | |
| Osteoporosis prevalence | 21.7% | 10.1% | 2.44 (1.25–4.99) | |
| 0.050.21520Odds ratio (log scale) |
Muscle function and bone mineral density (BMD)
- CKD: weaker handgrip strength, poorer chair-stand performance and slower gait speed vs controls
- BMD reduced in CKD
Original publication
High prevalence of sarcopenia, osteoporosis and osteosarcopenia in patients with chronic kidney disease compared with healthy controls. Osteoporos Int. Published 20 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →