Glycaemic Control According to the Final Insulin Dose Using an Innovative Fixed‐Dose Titration of Weekly Insulin Efsitora in Insulin‐Naïve Type 2 Diabetes
Authors' conclusion
In QWINT-1, the innovative fixed-dose efsitora simple titration resulted in effective HbA1c lowering for all fixed doses. Rates of clinically meaningful hypoglycaemia were low after fixed-dose increases.
Study context
- Population
- Insulin-naïve adults with T2D treated with once-weekly efsitora in QWINT-1efsitora-treated
- Participants
- 303 adults
- Comparison
- Efsitora-treated participants by final insulin dose at week 52
Methodological detailsphase 3, fixed-dose titration regimen
- Phase 3
- Fixed-dose titration regimen
Primary result
As reported in the abstract
Week 52
Participants remaining on a fixed efsitora dose
76%
All efsitora fixed-doses: robust HbA1c lowering, mean final HbA1c
< 7.0%
Safety
Combined level 2 and 3 hypoglycaemia within 4-week periods after an efsitora fixed-dose increase
- Estimated rates
- < 0.5 events/year
Original publication
Glycaemic Control According to the Final Insulin Dose Using an Innovative Fixed‐Dose Titration of Weekly Insulin Efsitora in Insulin‐Naïve Type 2 Diabetes. Diabetes Obes Metab. Published 3 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →