Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post‐Fracture Treatment, and All‐Cause Mortality
Authors' conclusion
Substantial variations exist in the global epidemiology of hip fractures and postfracture outcomes.
Study context
- Population
- Patients aged ≥50 years hospitalized with a hip fracture, 2005–2018, 19 countries and regionship fractures, 20 databases
- Participants
- 4,115,046 patients
- Outcome
- Age- and sex-standardized incidence rates of hip fractures; post-hip fracture anti-osteoporosis treatment; all-cause mortality after hip fracture
Methodological detailspatient-level healthcare data, standardized protocol and common data model, 19 countries and regions, 20 databases
- Patient-level healthcare data
- Standardized protocol and common data model
- 19 countries and regions
- 20 databases
Main finding
As reported in the abstract
Age- and sex-standardized hip fracture incidence per 100,000 population
Lowest incidence: Brazil
95.1
95% CI 94.8–95.4
Highest incidence: Denmark
315.9
95% CI 314.0–317.7
Observational data: associations, not effects.
Further findings
Projected annual number of hip fractures · 2018 to 2050
- Estimated total annual number nearly doubled from 2018 to 2050
Post-hip fracture anti-osteoporosis treatment · within 1 year
- Lowest: Germany
- 11.5% (95% CI 11.1% to 11.9%)
- Highest: UK
- 50.3% (95% CI 50.0% to 50.7%)
All-cause mortality · within 1 year
- Lowest: Singapore
- 14.4% (95% CI 14.0% to 14.8%)
- Highest: UK
- 28.3% (95% CI 28.0% to 28.6%)
Sex differences
- Males had lower anti-osteoporosis medication use than females, higher all-cause mortality, and a larger increase in projected hip fractures by 2050
Original publication
Global Epidemiology of Hip Fractures: Secular Trends in Incidence Rate, Post‐Fracture Treatment, and All‐Cause Mortality. J Bone Miner Res. Published 29 May 2023. doi:10. 1002/ jbmr. 4821
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