Endocrine oncology

Fear of Cancer Recurrence in Differentiated Thyroid Cancer Survivors: A Systematic Review

ThyroidPublished Systematic review

Authors' conclusion

FCR is common in thyroid cancer survivors, but significant heterogeneity in the current evidence base limits assessment of incidence, severity, or risk factors.

Study context

Population
DTC survivors; English literature, six electronic databases31 studies
Outcome
Incidence of fear of cancer recurrence (FCR)

Pooled result

As reported in the abstract

Incidence of FCR

Incidence of fear of cancer recurrence (FCR) (reported in 27/31 studies), range

15% to 91%

Further pooled results

Tools used to measure FCR

Validated tools used across all studies
8
Studies using self-developed nonvalidated items
5
Minimal repetition of validated tools; no clear consensus on a preferred survey tool

Factors influencing FCR

Studies reporting factors influencing FCR
11
Risk factors for increased FCR in >1 study: young age, upcoming clinical appointment
Protective in >1 article: male gender, higher education
No literature evaluating interventions to address FCR found

Original publication

Fear of Cancer Recurrence in Differentiated Thyroid Cancer Survivors: A Systematic Review. Thyroid. Published 18 March 2024. doi:10.1089/thy.2023.0642

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