Factors associated with successful weight loss after liraglutide treatment for obesity
Authors' conclusion
Slower GET1/2 and weight loss at 5 weeks predicted a weight loss of more than 4 kg at 16 weeks in all participants. Among liraglutide-treated adults, weight loss of more than 4 kg was associated with ad libitum meal kcal intake at 16 weeks.
Study context
- Population
- Obese adults (87% female)
- Participants
- 136 adults
- Comparison
- Liraglutide 3 mg SQ daily vs placebo; predictors of weight loss >4 kg
- Liraglutiden = 60
- Primary endpoint
- Variables associated with weight loss of more than 4 kg
- Follow-up
- 16 weeks
Methodological detailsplacebo-controlled, 16-week
- Placebo-controlled
- 16-week
Primary result
As reported in the abstract
Factors associated with weight loss >4 kg (final parsimonious model, all participants)
Final parsimonious model AUROC
0.832
GET1/2 at 5 weeks, OR per 50 minutes
2.505
95% CI 1.57–3.997
Kcal intake during ad libitum meal at 16 weeks, OR per 100 kcal
0.721
95% CI 0.602–0.864
Further findings
Weight loss >4 kg · 16 weeks
Liraglutide-treated only: kcal intake at 16 weeks associated with 4-kg weight loss
- AUROC
- 0.757
Original publication
Factors associated with successful weight loss after liraglutide treatment for obesity. Diabetes Obes Metab. Published 24 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →