Type 2 & other diabetes

Evaluation of a digital tool supporting therapeutic decision making for the personalized management of patients with type 2 diabetes not treated with insulin: A pilot study

Diabetes Res Clin PractPublished Randomised controlled trial

Authors' conclusion

When performed in a structured manner and used to modify the diabetes therapy through an algorithm-driven digital tool, SMBG can lead to significant improvements of glycemic control and variability in patients with type 2 diabetes not treated with insulin.

Study context

Population
Patients with non-insulin-treated T2D and inadequate glucose control; age 64.3 ± 9.4 years, disease duration 13.2 ± 9.1 years, HbA1c 7.8 ± 0.6%completed the study
Participants
82 patients
Comparison
Personalized Treatment Tool vs control
  • Personalized Treatment Tool (PTT)n = 41
  • Controln = 41reference
Methodological detailscluster-randomized, single-center, 16-week
  • Cluster-randomized
  • Single-center
  • 16-week

Primary result

As reported in the abstract

Changes in indicators of glucose control and variability · 16 weeks
  • Changes in indicators of glucose control and variability were not statistically different between the two groups

Further findings

Subgroup on a single anti-diabetes drug at baseline: changes in HbA1c, CGM-derived TIR 70-140 mg/dl, 24-hour MSG, GRADE and HBGI · 16 weeks

Significantly improved with PTT (n=9) vs control (n=14)

Original publication

Evaluation of a digital tool supporting therapeutic decision making for the personalized management of patients with type 2 diabetes not treated with insulin: A pilot study. Diabetes Res Clin Pract. Published 20 July 2023. doi:10.1016/j.diabres.2023.110836

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