Evaluating Eating Behaviour, Energy Homeostasis, and Obesity in Childhood-Onset Craniopharyngioma: A Feasibility Study
Authors' conclusion
These findings demonstrate that eating behaviour research is feasible and acceptable to craniopharyngioma patients and there is an association between BMISDS and hyperphagia in patients. Thus, food approach and avoidance behaviours may be useful targets for interventions to manage obesity in this patient group.
Study context
- Population
- Patients with childhood-onset craniopharyngioma (median age 14 years; 5 F/6 M) and matched controls (median age 12 years; 5 F/6 M); all patients had surgery, 9/11 also radiotherapy
- Comparison
- Childhood-onset craniopharyngioma patients vs matched controls
- Patientsn = 11
- Outcome
- Feasibility and acceptability of eating behaviour measures
Methodological detailsmatched controls
- Matched controls
Main finding
As reported in the abstract
Feasibility and acceptability
- Included measures were deemed highly tolerable by participants and their parent/carers
Further findings
| Outcome | Cliff's delta |
|---|---|
| HyperphagiaPreliminary data | 0.5 |
Hyperphagia vs body mass index standard deviation score (BMISDS) in patients
- Kendall's tau, hyperphagia with BMISDS in patients
- τ = 0.46
- Preliminary data
Hypothalamic damage post-surgery (Paris grading), patients
- Grade 2
- n = 6
- Grade 1
- n = 1
- Grade 0
- n = 2
Original publication
Evaluating Eating Behaviour, Energy Homeostasis, and Obesity in Childhood-Onset Craniopharyngioma: A Feasibility Study. Horm Res Paediatr. Published 17 May 2023. doi:10.
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