Ethnicity and socioeconomic status do not influence glycaemic outcomes of a tubeless hybrid closed‐loop system (Omnipod® 5) in adults with type 1 diabetes
Authors' conclusion
Early real-world use of a tubeless HCL system demonstrated significant and equal glycaemic improvements in diverse ethnic and socioeconomic groups. Promoting universal access to HCL technologies in T1D is therefore essential to ensure existing disparities in glycaemic outcomes are minimised.
Study context
- Population
- Adults with T1D initiating tubeless hybrid closed-loop (HCL) (Omnipod 5) at a large publicly funded multi-site diabetes service; 26.9% non-White; 48.8% in the two most deprived IMD quintiles
- Participants
- 160 adults
- Exposure
- Baseline vs 12 weeks after HCL (Omnipod 5) initiation; subgroups by ethnicity and socioeconomic status
- Outcome
- Mean TIR (3.9-10 mmol/L)
- Follow-up
- 12 weeks post-initiation
Methodological detailsreal-world, multi-site
- Real-world
- Multi-site
Main finding
As reported in the abstract
baseline to 12 weeks
Mean TIR, baseline
52.7 ± 16%
Mean TIR, 12 weeks
67.9 ± 12.7%
p < 0.001
Observational data: associations, not effects.
Further findings
White vs Non-White
| Outcome | White | Non-White | P value |
|---|---|---|---|
| Change in mean TIR by ethnic group | mean +14.8% (95% CI (12.6%, 17.3%)) | mean + 16.1% (95% CI 12.4%–19.7%) | P = 0.488 |
Lower socioeconomic vs Higher socioeconomic
| Outcome | Lower socioeconomic | Higher socioeconomic | P value |
|---|---|---|---|
| Change in mean TIR by socioeconomic group | mean + 15.9% (95% CI 13.3%–18.6%) | mean + 14.2% (95% CI 11.2%–17.1%) | P = 0.290 |
Baseline glycaemia
- Those with poorer baseline glycaemia experienced greater improvements
Original publication
Ethnicity and socioeconomic status do not influence glycaemic outcomes of a tubeless hybrid closed‐loop system (Omnipod® 5) in adults with type 1 diabetes. Diabetes Obes Metab. Published 9 July 2025. doi:10. 1111/ dom. 16553
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