Ethnic differences in risk of renal disease progression amongst young-onset type 2 diabetes in New Zealand
Authors' conclusion
Pacific and Māori with young-onset type 2 diabetes face a disproportionately higher DKD risk.
Study context
- Population
- Young adults 18–40 years with young-onset T2D in a New Zealand (NZ) primary care cohort (1994–2018); 46 % Pacific, 31 % Māori, 23 % NZ European; 54 % female; mean age 33.9 ± 4.9 years; mean BMI 38.0 ± 8.7 kg/m²; diabetes duration 1.7 years
- Participants
- 2,184 adults
- Comparison
- Pacific people and Māori vs NZ European
- Primary endpoint
- Elevated DKD risk, classified using Urine Albumin-Creatinine Ratio (UACR) and Estimated Glomerular Filtration Rate (eGFR), with hyperfiltration (eGFR ≥ 120 mL/min/1.73 m²) as an early marker
Primary result
As reported in the abstract
Elevated DKD risk
Estimate (95 % CI)P value
Pacificvs NZEp for difference across ethnic groups
aOR 1.96(1.50–2.57)
P < 0.001Māorivs NZE
aOR 1.41(1.06–1.87)
Māorivs Pacificless risk with Māori
OR 0.72(0.58–0.89)
Further findings
Independent predictors of Diabetic Kidney Disease (DKD) risk
- Independent predictors: ethnicity, TG-HDL ratio, systolic blood pressure, antihypertensive use and HbA1c
- BMI was not significant
Original publication
Ethnic differences in risk of renal disease progression amongst young-onset type 2 diabetes in New Zealand. Diabetes Res Clin Pract. Published 24 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →