EndoCompass project: endocrinology across the lifespan
Authors' conclusion
This component of the EndoCompass project provides an evidence-based roadmap for understanding hormone regulation across life stages. The analysis demonstrates the need for coordinated research spanning conception to aging to address Europe's demographic challenges. The findings support strategic investment in lifespan approaches to endocrine health.
Study context
- Population
- Endocrine research across the lifespan, from gametogenesis through embryonic development, early life, puberty, adulthood and aging
- Outcome
- Research priorities
Methodological detailsdatabase analysis and expert analysis, analysis of European Union (EU) CORDIS database (Horizon 2020, 2014-2020), Joint initiative of the European Society of Endocrinology and the European Society of Paediatric Endocrinology
- Database analysis and expert analysis
- Analysis of EU CORDIS database (Horizon 2020, 2014-2020)
- Joint initiative of the European Society of Endocrinology and the European Society of Paediatric Endocrinology
Main finding
As reported in the abstract
- Understanding epigenetic programming from embryonic life
- Elucidating developmental origins of adult disease
- Investigating brain-gut communication across ages
- Addressing endocrine aspects of healthy aging
- Special emphasis on critical developmental windows, transgenerational effects, and integrated research spanning paediatric and adult endocrinology
Observational data: associations, not effects.
Original publication
EndoCompass project: endocrinology across the lifespan. Eur J Endocrinol. Published 17 October 2025. doi:10. 1093/ ejendo/ lvaf074
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