Effects of Whole‐Body Cryotherapy Combined With Conventional Obesity Management Versus Obesity Management Alone: A Clinical Trial
Authors' conclusion
WBC did not significantly enhance weight loss, activate BAT, or alter most metabolic responses during conventional obesity management. Further research is needed to confirm whether WBC benefits glucose and cholesterol metabolism.
Study context
- Population
- Adults with obesity
- Participants
- 19 adults
- Comparison
- Whole-body cryotherapy (WBC) combined with lifestyle-based obesity management vs obesity management alone
- CRYOn = 10
- CONn = 9reference
- Outcome
- Weight loss
- Follow-up
- 5 and 12 months
Main finding
As reported in the abstract
Weight loss at 5 months: CRYO vs CON
11.9% vs 11.5%
Weight loss at 12 months: CRYO vs CON
9.9% vs 8.0%
Secondary outcomes
| Outcome | Difference (mmol/L) | P value |
|---|---|---|
| Fasting glucose reduction · 5 monthsGreater reduction with CRYO | 0.41 | P = 0.026 |
| LDL-C reduction · 5 monthsGreater reduction with CRYO | 0.44 | P = 0.034 |
Brown adipose tissue (BAT) glucose uptake, energy expenditure, adipose tissue transcriptomics, skeletal muscle proteomics changes
- No significant between-group differences
Original publication
Effects of Whole‐Body Cryotherapy Combined With Conventional Obesity Management Versus Obesity Management Alone: A Clinical Trial. Obesity (Silver Spring). Published 3 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →