Diabetes foot complications and standardized mortality rate in type 2 diabetes
Authors' conclusion
Patients with T2D but without a foot complication have an SMR_IMD that is only slightly higher than that of the general population. Those diagnosed with a foot complication have a mortality risk that is double that of those without T2D.
Study context
- Population
- Individuals with T2D, Salford Integrated Care Record (Salford, UK), 2010–202011,806 T2D included
- Participants
- 9,857 vs 2,979
- Exposure
- Foot complication vs no foot complication
- No foot complicationsn = 9,857reference
- Foot complicationn = 2,979
- Outcome
- Mortality: SMR adjusted for index of multiple deprivation (SMR_IMD)
- Follow-up
- 2010-2020
Methodological detailspopulation-based, index of multiple deprivation (IMD)-adjusted standardized mortality ratio
- Population-based
- IMD-adjusted standardized mortality ratio
Main finding
As reported in the abstract
SMR_IMD
| Group | Value | LYLD |
|---|---|---|
| No foot complications | 1.13 | 2.74 |
| Foot complication | 2.29 |
Value
No foot complications1.13
Foot complication2.29
LYLD
No foot complications2.74
Foot complication— not stated in the abstract
- Overall T2D SMR_IMD (excess deaths 1326)
- 1.51
Observational data: associations, not effects.
Further findings
Death in patients with foot complication, multivariate analysis
- OR for death, albumin-to-creatinine ratio >3 mg/mmol
- 1.93
- OR for death, eGFR <60 mL/min/1.73m2
- 1.92
HbA1c >58 mmol/mol
- Little difference with a foot complication
Original publication
Diabetes foot complications and standardized mortality rate in type 2 diabetes. Diabetes Obes Metab. Published 18 September 2023. doi:10.
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