Type 2 & other diabetes

Development and first‐stage validation of a digital version of the Digit Symbol Substitution test for use in assessing cognitive function in older people with diabetes

Diabetes Obes MetabPublished Diagnostic accuracy study

Performance · Correlation between P&P and digital DSSTResult — go to the resultr 0.76

Authors' conclusion

This study describes the development of and provides first-stage validation data for a newly developed digital cognitive assessment tool that may be used for screening and surveillance of cognitive function in older people with diabetes. More studies are needed to further validate this tool, especially when self-administered and in different clinical settings.

Study context

Population
Individuals with T2D aged ≥60 years; one-time meeting with both versions administeredinvited
Participants
100 individuals
Comparison
Digital digit symbol substitution test (DSST) vs pencil-and-paper DSST
Outcome
Correlation between digital and P&P versions of the DSST
Methodological detailsdevelopment and first-stage validation, machine-learning algorithm
  • Development and first-stage validation
  • Machine-learning algorithm

Performance

Correlation between P&P and digital DSST

r

0.76

P < 0.001

As reported in the abstract

Further findings

OutcomeDigital DSST
ML model accuracy
Overall accuracy89.1%

Correlation between machine-learning (ML) model and manual reading of digital DSST

Correlation ML model vs manual reading of digital DSST (r)
0.99
  • p < 0.001

Original publication

Development and first‐stage validation of a digital version of the Digit Symbol Substitution test for use in assessing cognitive function in older people with diabetes. Diabetes Obes Metab. Published 17 May 2024. doi:10.1111/dom.15657

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