Obesity

Cost‐Effectiveness of Two Iterations of a Community‐Based Cardiovascular Disease Prevention Intervention

Obesity (Silver Spring)Published Cost-effectiveness analysis of two randomised trials

Authors' conclusion

SHHC-2.0 compared favorably to SHHC-1.0 and could be cost-effective for longer-term effects. Results can help guide policy makers' decisions on larger-scale community-based obesity and cardiovascular disease prevention interventions.

Study context

Population
Women ≥40 years with obesity, or sedentary with overweight, from rural medically underserved towns
Comparison
Strong Hearts, Healthy Communities (SHHC) intervention vs control
Methodological detailsQuality-adjusted life year (QALY) cost-effectiveness analysis (CEA) for hypothetical national cohort of 2.2 million women, 10-year horizon
  • QALY CEA for hypothetical national cohort of 2.2 million women
  • 10-year horizon

Primary result

As reported in the abstract

SHHC-1.0 resource cost per participant
$775
SHHC-2.0 resource cost per participant
$747
ICER, payer's perspective, SHHC-1.0, per kg weight loss
$346
ICER, payer's perspective, SHHC-2.0, per kg weight loss, 24 weeks
$187
ICER, payer's perspective, SHHC-2.0, per kg weight loss, 48 weeks
$155

Further findings

Cost to avert QALYs lost · 10-year horizon

SHHC-1.0, societal perspective
$238,271
SHHC-1.0, health care sector perspective
$62,646
SHHC-2.0 at 24 weeks, societal perspective
$214,257
SHHC-2.0 at 24 weeks, health care sector perspective
$67,747
SHHC-2.0 at 48 weeks, societal perspective
$94,395
SHHC-2.0 at 48 weeks, health care sector perspective
$11,341
  • Hypothetical cohort of 2.2 million women

Original publication

Cost‐Effectiveness of Two Iterations of a Community‐Based Cardiovascular Disease Prevention Intervention. Obesity (Silver Spring). Published 16 October 2025. doi:10.1002/oby.70050

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