Cost‐Effectiveness Analysis of an Intensive Lifestyle Intervention Versus Usual Care for Latino Youth With Prediabetes
Authors' conclusion
Among Latino youth with prediabetes, an intensive lifestyle intervention resulted in a nonsignificant reduction in 2-h glucose at a higher cost compared with usual care.
Study context
- Population
- Latino youth ages 12–16 years with obesity and prediabetes
- Participants
- 79 vs 38
- Comparison
- 6-month intensive lifestyle intervention vs usual care
- Intervention (INT)n = 79
- Usual care (UC)n = 38reference
- Primary endpoint
- Cost and incremental cost-effectiveness ratio (ICER) of the intervention vs usual care
Methodological detailshealth care, family and total societal perspectives, 2019 US Dollars, Conducted May 2016 to March 2020
- Health care, family and total societal perspectives
- 2019 US Dollars
- Conducted May 2016 to March 2020
Primary result
As reported in the abstract
Societal cost per participant · first 6 months
INT
$1935.21
CI $1583.12, $2315.05
UC
$234.20
CI $190.71, $278.61
- Incremental cost-effectiveness ratio (ICER) for 2-h glucose, INT vs UC, at 6 months
- $222.78 per mg/dL
Further findings
| Outcome | Difference (mg/dL) (95% CI) | |
|---|---|---|
| Between-group difference in change in 2-h post-challenge glucose · 6 months | 7.2 (−5.3 to 19.7) | |
| Between-group difference in change in 2-h post-challenge glucose · 12 months | 0.3 (−14.1 to 14.5) | |
| −20−1001020Difference, mg/dL (linear scale) |
| Outcome | UC |
|---|---|
| Societal cost per participant · entire 12 months | $468.40 (CI $379.19, $568.37) |
- Societal cost per participant — ICER for 2-h glucose, INT vs UC, at 12 months
- $4816.57 per mg/dL
Societal cost per participant · entire 12 months
- No additional costs for INT after the first 6 months
Original publication
Cost‐Effectiveness Analysis of an Intensive Lifestyle Intervention Versus Usual Care for Latino Youth With Prediabetes. Pediatr Obes. Published 31 July 2025. doi:10.
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