Contemporary automated insulin delivery systems in older adults with type 1 diabetes: A systematic review and meta-analysis
Authors' conclusion
Findings were consistent in direction with broader AID literature.
Study context
- Population
- Adults aged ≥60 years with T1D9 studies (7 observational, 2 randomized crossover)
- Participants
- 8,765 adults
- Outcome
- Glycaemic outcomes during AID use (pooled)
Methodological detailssingle-arm random-effects meta-analyses, change-from-baseline analyses, Searched PubMed, Embase, Web of Science, Cochrane Library, ClinicalTrials.gov through February 2026
- Single-arm random-effects meta-analyses
- Change-from-baseline analyses
- Searched PubMed, Embase, Web of Science, Cochrane Library, ClinicalTrials.gov through February 2026
Pooled result
As reported in the abstract
Pooled mean time in range (TIR)
77.95%
95% CI 75.31–80.59
Pooled HbA1c, 6.95% (52 mmol/mol)
6.95%
95% CI 6.67–7.24
Pooled time below range (TBR) <70 mg/dL
1.35%
95% CI 1.12–1.57
Further pooled results
| Outcome | MD (%) (95% CI) |
|---|---|
| Change from baseline with AID useHbA1c change from baseline | - 0.36 (- 0.63 to - 0.09) |
Change from baseline with automated insulin delivery (AID) use
- Higher TIR, lower hyperglycaemia, lower diabetes distress, without increased hypoglycaemia
Original publication
Contemporary automated insulin delivery systems in older adults with type 1 diabetes: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 11 August 2026. doi:10.
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