Comparison of Point Accuracy Between Two Widely Used Continuous Glucose Monitoring Systems
Authors' conclusion
The FreeStyle Libre 3 sensor was more accurate than the Dexcom G7 sensor in all metrics evaluated throughout the study period. This is the first head-to-head study to our knowledge that compares the flagship products currently in widespread use of the two largest CGM manufacturers.
Study context
- Population
- Adults (≥ 18 years) with diagnosed T1D or T2Dincluded in analysis
- Participants
- 55 adults
- Comparison
- FreeStyle Libre 3 vs Dexcom G7 Continuous Glucose Monitoring (CGM) sensors
- Outcome
- Differences in MARD vs laboratory reference (YSI) and capillary blood glucose values; number and percentage of matched glucose pairs within ±20 mg/dL/±20 of reference across glucose ranges (< 54, 54 to 69, 70 to 180, 181 to 250, > 250 mg/dL) and combined
Methodological detailsmulticenter, single-arm, prospective, nonsignificant risk evaluation, head-to-head comparison
- Multicenter
- Single-arm
- Prospective
- Nonsignificant risk evaluation
- Head-to-head comparison
Performance
As reported in the abstract
MARD
MARD
Glucose values within ±20 mg/dL/±20 of reference
- FreeStyle Libre 3 vs Dexcom G7: P < 0.0001 — mean absolute relative difference (MARD) significantly lower with FreeStyle Libre 3
Further findings
MARD during next 12 hours
P < 0.0001
- MARD during next 12 hours: MARD lower with FreeStyle Libre 3, also throughout the study period
MARD during first 12 hours
- MARD values for both CGM sensors were similar during the first 12 hours
Original publication
Comparison of Point Accuracy Between Two Widely Used Continuous Glucose Monitoring Systems. J Diabetes Sci Technol. Published 8 January 2024. doi:10.
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