Thyroid disease

Comparison of Perioperative Outcomes in Patients with Graves' Disease Undergoing Total Thyroidectomy With or Without Near Infrared Autofluorescence Imaging

ThyroidPublished Retrospective before-and-after study

Authors' conclusion

The rate of incidental parathyroidectomy on final pathology was lower with use of NIRAF, without an impact on temporary or permanent hypocalcemia rates compared to conventional technique.

Study context

Population
Patients with GD undergoing total thyroidectomy at a single center
Participants
85 vs 100
Exposure
Total thyroidectomy (TT) with near-infrared autofluorescence (NIRAF) imaging vs TT without NIRAF imaging
  • NIRAFn = 85
  • non-NIRAFn = 100reference
Outcome
Incidence of temporary hypocalcemia
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Temporary hypocalcemia

P = 0.66

Observational data: associations, not effects.

Secondary outcomes

Incidental parathyroidectomy on final pathology

P = 0.002

Permanent hypocalcemia · similar between groups

P = 0.66

Intraoperative parathyroid implantation

P = 0.02

Median

OutcomeNIRAFnon-NIRAFP value
Parathyroid glands identified intraoperatively33P = 0.47

Original publication

Comparison of Perioperative Outcomes in Patients with Graves' Disease Undergoing Total Thyroidectomy With or Without Near Infrared Autofluorescence Imaging. Thyroid. Published 11 December 2023. doi:10.1089/thy.2023.0360

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