Comparison of Perioperative Outcomes in Patients with Graves' Disease Undergoing Total Thyroidectomy With or Without Near Infrared Autofluorescence Imaging
Authors' conclusion
The rate of incidental parathyroidectomy on final pathology was lower with use of NIRAF, without an impact on temporary or permanent hypocalcemia rates compared to conventional technique.
Study context
- Population
- Patients with GD undergoing total thyroidectomy at a single center
- Participants
- 85 vs 100
- Exposure
- Total thyroidectomy (TT) with near-infrared autofluorescence (NIRAF) imaging vs TT without NIRAF imaging
- NIRAFn = 85
- non-NIRAFn = 100reference
- Outcome
- Incidence of temporary hypocalcemia
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Temporary hypocalcemia
P = 0.66
Observational data: associations, not effects.
Secondary outcomes
Incidental parathyroidectomy on final pathology
P = 0.002
Permanent hypocalcemia · similar between groups
P = 0.66
Intraoperative parathyroid implantation
P = 0.02
Median
| Outcome | NIRAF | non-NIRAF | P value |
|---|---|---|---|
| Parathyroid glands identified intraoperatively | 3 | 3 | P = 0.47 |
Original publication
Comparison of Perioperative Outcomes in Patients with Graves' Disease Undergoing Total Thyroidectomy With or Without Near Infrared Autofluorescence Imaging. Thyroid. Published 11 December 2023. doi:10. 1089/ thy. 2023. 0360
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