Comparison and assessment of anthropometric index with risk of type 2 diabetes mellitus: two prospective cohort studies in China
Authors' conclusion
Abdominal adiposity indices have significant value in predicting T2DM risk, with notable sex-specific differences. Among these, RFM were better predictors in both women and men. These findings suggest that abdominal obesity indices could be used to inform prevention strategies.
Study context
- Population
- Participants of the Shanghai Men's and Women's Health Studies, China
- Participants
- 71,356 vs 56,288
- Exposure
- 17 anthropometric indices and T2D risk
- Womenn = 71,356
- Menn = 56,288
- Outcome
- Associations of 17 anthropometric indices with T2D risk and their predictive value
Methodological detailstwo prospective cohorts, Cox regression for hazard ratios (HRs); ROC curves for predictive performance; subgroup and sensitivity analyses
- Two prospective cohorts
- Cox regression for HRs; ROC curves for predictive performance; subgroup and sensitivity analyses
Main finding
As reported in the abstract
Relative fat mass (RFM) · mean follow-up 17.42 (women) and 12.35 (men) years
Hazard ratio per SD (95% CI)
Women
2.42(2.34–2.49)
Men
2.22(2.13–2.31)
Observational data: associations, not effects.
Original publication
Comparison and assessment of anthropometric index with risk of type 2 diabetes mellitus: two prospective cohort studies in China. Diabetes Res Clin Pract. Published 27 January 2026. doi:10.
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