Closed-loop insulin delivery systems in patients with pancreatitis or pancreatectomy-induced diabetes: A case series
Study context
- Population
- Adults with pancreatitis or pancreatectomy-induced diabetes; mean ± SD age 59 ± 12
- Participants
- 10 adults
- Exposure
- Hybrid closed-loop (HCL) insulin delivery vs before HCL insulin delivery
- Outcome
- Long-term metabolic control
- Follow-up
- Median 346 days (range 64 - 631) with HCL
Main finding
As reported in the abstract
CGM TIR [70-180 mg/dl] · median 346 days (range 64 - 631)
P = 0. 049
Observational data: associations, not effects.
Further findings
Time-below-range [<70 mg/dl] on CGM · median 346 days (range 64 - 631)
P = 0.142
Mean
| Outcome | HCL | Before HCL | P value |
|---|---|---|---|
| Coefficient of glucose variability · median 346 days (range 64 - 631) | 35.4 (SD 7.6) | 37.8 (SD 7.1) | P = 0.047 |
HbA1c
- HbA1c decreased
- P = 0.076
Safety
- Acute adverse metabolic events — HCL
- 0 events
Original publication
Closed-loop insulin delivery systems in patients with pancreatitis or pancreatectomy-induced diabetes: A case series. Diabetes Metab. Published 24 May 2024. doi:10.
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