Obesity

Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection

Int J Obes (Lond)Published Cohort study

Authors' conclusion

After 3 years follow-up survivors of CC accumulated abdominal adipose tissue. Notably, those who underwent left-sided colonic resection had increased VAT and SAT, whereas those who underwent right-sided colonic resection demonstrated solely increased SAT.

Study context

Population
Patients with stage I–III colon cancer undergoing cancer surgery; Computed tomography (CT) at L3-level preoperatively and 3 years after surgery
Participants
134 patients
Exposure
Left-sided vs right-sided colonic resection
Outcome
Change in abdominal VAT
Follow-up
3 years

Main finding

As reported in the abstract

Left-sided resection: increase in visceral adipose tissue (VAT)

5%

95% CI 2–9%p < 0.01

Observational data: associations, not effects.

Further findings

Change in subcutaneous adipose tissue (SAT) · 3 years

Left-sided resection: increase in SAT
4% (95% CI: 2-6%, p < 0.001)
Right-sided resection: increase in SAT
6% (95% CI: 4-9%, p < 0.001)

Change in total adipose tissue (TAT) · 3 years

Left-sided resection: increase in TAT
5% (95% CI: 2-7%, p < 0.01)
Right-sided resection: increase in TAT
4% (95% CI: 1-7%, p < 0.01)

Change in VAT by sex · 3 years

Only males with left-sided resection had a significant VAT increase
6% (95% CI: 2-10%, p < 0.01)

Original publication

Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection. Int J Obes (Lond). Published 3 January 2024. doi:10.1038/s41366-023-01445-8

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