Burden of long‐term conditions and management of people with overweight and obesity: Data from the United Kingdom primary care cohort of the IMPACT ‐O study
Authors' conclusion
Results confirm the high burden of ORCs in adults at first identification of overweight or obesity in primary care and the limited use of pharmacotherapy and bariatric surgery; this suggests a need to evaluate treatment strategies and support for people with overweight and obesity in the UK.
Study context
- Population
- Adults (≥18 years) in UK primary care (IQVIA Medical Research Database, The Health Improvement Network), 2018–2022three cohorts
- Participants
- 73,279 / 62,226 / 343,755
- Exposure
- Overweight/obesity vs Obesity vs Intervention
- Overweight/obesityn = 73,279
- Obesityn = 62,226
- Interventionn = 343,755
- Outcome
- ≥1 obesity-related complication (ORC)
Methodological detailsmulti-country, electronic medical records, UK primary care cohort
- Multi-country
- Electronic medical records
- UK primary care cohort
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Management in the intervention cohort
- Lifestyle interventions
- 96.8%
- GLP-1 RA
- 3.6%
- Orlistat
- 2.5%
- Bariatric surgery
- 0.3%
Original publication
Burden of long‐term conditions and management of people with overweight and obesity: Data from the United Kingdom primary care cohort of the IMPACT ‐O study. Diabetes Obes Metab. Published 17 December 2025. doi:10.
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