Bidirectional associations between adiposity and mental health: a prospective cohort study of the UK Biobank
Authors' conclusion
The bidirectional associations between specific indicators of adiposity and mental health depend on the types of adiposity.
Study context
- Population
- UK Biobank participants
- Participants
- 60,319 participants
- Outcome
- Bidirectional associations between adiposity indicators and mental health
Methodological detailslongitudinal, UK Biobank
- Longitudinal
- UK Biobank
Main finding
As reported in the abstract
- BMI and general obesity were bidirectionally associated with recent depressive symptoms, probable depression, experiencing at least one type of stress (especially from serious illness, injury or assault to oneself, or financial difficulties) and life satisfaction (especially health and financial situation satisfaction)
- Waist circumference and abdominal obesity were bidirectionally associated with recent depressive symptoms and financial situation satisfaction
- Body fat percentage and high body fat percentage were bidirectionally associated with recent depressive symptoms, stress from financial difficulties, health satisfaction and financial situation satisfaction
- Multivariate logistic regressions and mixed-effects models
Observational data: associations, not effects.
Original publication
Bidirectional associations between adiposity and mental health: a prospective cohort study of the UK Biobank. Obesity (Silver Spring). Published 1 May 2025. doi:10. 1002/ oby. 24296
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