Autonomously functioning thyroid nodules present intermediate malignancy risk according to European Thyroid Imaging Reporting and Data System (EU-TIRADS) and yield indeterminate cytology results
Authors' conclusion
Of the 67 AFTN evaluated in this study, 50% presented with normal serum TSH, 70% displayed ultrasound features suggesting an intermediate malignancy risk and 50% of the AFTN submitted to cytology yielded indeterminate results. No malignant AFTN was detected.
Study context
- Population
- Consecutive patients referred for thyroid workup with autonomously functioning thyroid nodules (AFTN), March 2018–September 2021AFTN of 901 referred
- Participants
- 67 patients
- Outcome
- Clinical, US, cytological and histological characteristics of AFTN
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
- Euthyroid
- More than half
- Serum TSH, median (IQR)
- 0.41 (0.03-0.97) mU/L
- AFTN size by ultrasound (US), median (IQR)
- 27.0 (21.1-35.0) mm
- EU-TIRADS score 3
- 28.4%
- EU-TIRADS score 4
- 71.6%
- Indeterminate fine needle aspiration (FNA) results (of 47 AFTN with cytology)
- 24 (51%)
Observational data: associations, not effects.
Original publication
Autonomously functioning thyroid nodules present intermediate malignancy risk according to European Thyroid Imaging Reporting and Data System (EU-TIRADS) and yield indeterminate cytology results. Eur Thyroid J. Published 20 December 2023. doi:10.
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