Associations of radiologic characteristics of the neonatal hypothalamus with early life adiposity gain
Authors' conclusion
This finding supports the notion that underlying processes in the MBH may play a role in early life growth and, by extension, childhood obesity risk.
Study context
- Population
- Full-term healthy neonatesup to n = 35
- Participants
- 35 neonates
- Outcome
- Association of MRI evidence of MBH gliosis (neonatal T2 signal) with change in body fat percentage measured by DXA
- Follow-up
- Neonatal to six months
Main finding
As reported in the abstract
Neonatal MBH T2 signal and change in body fat percentage · six months
- Neonatal T2 signal in the mediobasal hypothalamus (MBH) was positively associated with six-month changes in body fat percentage
Observational data: associations, not effects.
Original publication
Associations of radiologic characteristics of the neonatal hypothalamus with early life adiposity gain. Pediatr Obes. Published 13 March 2024. doi:10.
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