Association of anthropometric parameter with myopia in children and adolescents: A systematic review and meta-analysis
Authors' conclusion
Our findings support that anthropometric parameter was significantly associated with myopia in children and adolescents. However, given the limitations of the included cross-sectional studies, prospective studies are warranted to further investigate this issue.
Study context
- Population
- Children and adolescents aged 0–25 years; databases searched from inception to June, 2025
- Participants
- 1,505,099 children18 cross-sectional studies
- Comparison
- Overweight, obesity and body mass index (BMI)/WWI vs reference
- Outcome
- Myopia
Pooled result
As reported in the abstract
Pooled odds ratio (95% CI)P value
OverweightI2 = 81.6%
1.27(1.08 ≈1.51)
P < 0.001ObesityI2 = 88.3%
1.25(1.12 ≈1.39)
P < 0.001Further pooled results
Myopia, overweight, after excluding outliers
| Pooled OR (95% CI) | P value | ||
|---|---|---|---|
| OverweightI2 = 0.0% | 1.14 (1.13 ≈1.15) | P = 0.444 | |
| 0.512Pooled odds ratio (log scale) |
| Outcome | Pooled value (95% CI) | P value |
|---|---|---|
| Myopia, BMI in BMI/WWI groupI2 = 88.9% | 1.08 (1.00 ≈1.18) | P < 0.001 |
Subgroup analyses (age, region, visual acuity method, sample, covariate adjustment, confounder control)
- Results inconsistent across subgroups
Heterogeneity and publication bias
- Publication year not a source of heterogeneity (meta-regression)
- No significant publication bias by Egger's test in overweight, obesity and BMI/WWI groups
Original publication
Association of anthropometric parameter with myopia in children and adolescents: A systematic review and meta-analysis. Int J Obes (Lond). Published 6 September 2025. doi:10.
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