Association between classes and subclasses of polyphenol intake and 5‐year body weight changes in the EPIC‐PANACEA study
Authors' conclusion
Higher intakes of flavonoids and their subclasses are inversely associated with a modest body weight change. Results regarding hydroxycinnamic acids in coffee consumers require further investigation.
Study context
- Population
- Men and women aged 25 to 70 years, EPIC-PANACEA project, nine European countries
- Participants
- 349,165 men
- Exposure
- Intake of total polyphenols, polyphenol classes and subclasses
- Outcome
- Body weight change
- Follow-up
- Median 5 years
Methodological detailsmulticentre (nine European countries), multilevel mixed linear regression
- Multicentre (nine European countries)
- Multilevel mixed linear regression
Main finding
As reported in the abstract
Total flavonoids intake, inverse association with body weight change
−0.195 kg/5 years
95% CI −0.262 to −0.128
Total polyphenols intake, positive association with body weight gain
0.205 kg/5 years
95% CI 0.138 to 0.272
Hydroxycinnamic acids intake, positive association with body weight gain
0.324 kg/5 years
95% CI 0.267 to 0.381
Observational data: associations, not effects.
Further findings
Overall weight change · median 5 years
- Average weight gain (±5.0 kg)
- 2.6 kg
Hydroxycinnamic acid intake and body weight gain, stratified by coffee consumption · median 5 years
kg/5 years
- Coffee consumers, positive association
- 0.379 (95% CI 0.319 to 0.440)
- Coffee nonconsumers, no association
- −0.179 (95% CI −0.490 to 0.133)
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →