Association between body shape index and arterial stiffness: results of the EVasCu study and a meta-analysis
Authors' conclusion
Based on both the results obtained in the EVasCu study and the meta-analysis, there is a positive association between ABSI and arterial stiffness, both in healthy subjects and in participants with comorbidities. For each unit of cm/kg/m²/m increase in ABSI, the risk of arterial stiffness increased by 112% for central arterial stiffness, 121% for peripheral arterial stiffness, and 199% for systemic arterial stiffness. However, further research is needed in this field of knowledge.
Study context
- Population
- Healthy subjects (EVasCu study); general population (meta-analysis)EVasCu study
- Participants
- 390 subjects
- Outcome
- Association between ABSI and arterial stiffness (a-PWv and CAVI)
Pooled result
As reported in the abstract
Correlation coefficient, a-PWv and ABSI (p < 0.01)
0.458
Correlation coefficient, cardio-ankle vascular index (CAVI) and ABSI (p < 0.01)
0.408
Further pooled results
Meta-analysis: pooled correlation coefficient of ABSI with arterial stiffness
- Central arterial stiffness, r
- 0.22 (95% CI 0.16, 0.28)
- Peripheral arterial stiffness, r
- 0.21 (95% CI 0.14, 0.28)
- Systemic arterial stiffness, r
- 0.28 (95% CI 0.21, 0.3)
Meta-analysis: pooled OR of arterial stiffness with ABSI
- Central arterial stiffness, OR
- 2.12 (95% CI 1.68, 2.56)
- Peripheral arterial stiffness, OR
- 2.21 (95% CI 1.81, 2.60)
- Systemic arterial stiffness, OR
- 2.99 (95% CI 2.14, 3.85)
Original publication
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