Assessment of left atrial function in patients with metabolic syndrome by four-dimensional automatic left atrial quantification
Authors' conclusion
4D-LAQ is capable of effectively assessing the LA function in MS patients and providing a useful reference for clinical diagnosis. SBP and TG serve as the independent correlative factors for LA function.
Study context
- Population
- Patients with metabolic syndrome and normal controls; Left atrial (LA) volume and strain assessed by 4D-LAQ
- Participants
- 110 vs 70
- Exposure
- Metabolic syndrome (MS) patients vs normal controls
- MSn = 110
- Controln = 70reference
- Outcome
- LA volume, strain parameters and LAEF
Main finding
As reported in the abstract
- LA volume parameters increased in MS vs control
- LA strain parameters and LA emptying fraction (LAEF) decreased in MS vs control (all P < 0.05)
Observational data: associations, not effects.
Further findings
Epicardial adipose tissue (EAT) thickness and LA strain
- EAT thickness associated with longitudinal strain (LASr), LAScd, LASr-c and LAScd-c (all P < 0.05)
- LASct and LASct-c not statistically significant
Independent correlates of LA strain in MS (linear regression)
- Systolic blood pressure (SBP) and triglyceride (TG) are independent correlative factors
Repeatability of 4D-LAQ
- Good intra- and inter-observer agreement
Original publication
Assessment of left atrial function in patients with metabolic syndrome by four-dimensional automatic left atrial quantification. Diabetes Res Clin Pract. Published 23 December 2023. doi:10.
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