Age of type 2 diabetes onset as a risk factor for dementia: A 13-year retrospective cohort study
Authors' conclusion
Later age at onset of diabetes is strongly associated with dementia. A better understanding of the diabetes-dementia relationship is needed to inform strategies for promoting specific healthcare pathways.
Study context
- Population
- Inhabitants of Romagna's catchment area, Italy, with estimated onset of T2D in 2008–2017, aged ≥ 55, follow-up until 2020
- Exposure
- Age at T2D onset: ≥75 and 65-74 vs 55-64 years
- Outcome
- Dementia risk (time to dementia from diabetes onset)
Methodological detailshealthcare administrative records, competing-risks analysis
- Healthcare administrative records
- Competing-risks analysis
Main finding
As reported in the abstract
Dementia-free survival (DFS) · end of follow-up
Observational data: associations, not effects.
Further findings
Clinical predictors of dementia
- More comorbidities at diabetes onset and initial treatment with ≥ 2 antidiabetics were clinical predictors
Original publication
Age of type 2 diabetes onset as a risk factor for dementia: A 13-year retrospective cohort study. Diabetes Res Clin Pract. Published 24 June 2024. doi:10.
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