Diabetes complications

A simple score-based strategy to improve equity of the UK biennial diabetic eye screening protocol among people deemed as low risk

DiabetologiaPublished Retrospective cohort study with simulation of screening protocols

Authors' conclusion

A simple, clinically deliverable, personalised protocol for identifying who should be screened annually or biennially for diabetic eye disease would improve equity in risk of delayed STDR diagnosis per appointment.

Study context

Population
People without DR on two consecutive screening visits (low risk), North East London Diabetic Eye Screening Programme, January 2012–September 2023
Participants
105,083 people
Exposure
Simplified score-based screening protocol vs biennial screening
Outcome
Delayed STDR diagnoses
Methodological detailslinked electronic health records (EHR) data, logistic regression, simplified points model, external validation (South East London DESP)
  • Linked EHR data
  • Logistic regression
  • Simplified points model
  • External validation (South East London DESP)

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Reduction in annual screening appointments

Incident sight-threatening diabetic retinopathy (STDR) among low-risk participants · mean 5.0 years (SD 3.4 years)

Incident STDR cases
3694

STDR risk by subgroup under biennial screening

Almost all groups had significantly higher STDR risk vs people aged ≥41 years, white ethnicity, diabetes <10 years

Original publication

A simple score-based strategy to improve equity of the UK biennial diabetic eye screening protocol among people deemed as low risk. Diabetologia. Published 12 March 2025. doi:10.1007/s00125-025-06379-6

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