A nomogram for predicting surgery outcome of tumor-induced osteomalacia: a case-control study
Authors' conclusion
This study established a prognostic model for the preoperative prediction of surgical outcomes for TIO. This model can be used as a reference in clinical practice for the development of individualized treatment strategies.
Study context
- Population
- Patients with tumor-induced osteomalacia (TIO) who underwent surgical treatment
- Participants
- 309 patients
- Comparison
- Nomogram derived in training set vs validation set
- Training setn = 222
- Validation setn = 87
- Outcome
- Surgical outcomes of patients with TIO
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Nomogram discrimination for surgical outcome
| Group | Value | p |
|---|---|---|
| Training set | C-index 0.864 | p < 0.001 |
| Validation set | AUC 0.782 | p < 0.001 |
Value
Training setC-index 0.864
Validation setAUC 0.782
p
Training setp < 0.001
Validation setp < 0.001
Observational data: associations, not effects.
Original publication
A nomogram for predicting surgery outcome of tumor-induced osteomalacia: a case-control study. Osteoporos Int. Published 18 September 2025. doi:10. 1007/ s00198-025-07686-9
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